Search results for "methods [Gene Expression Profiling]"
showing 10 items of 838 documents
First-principles modelling for time-resolved ARPES under different pump-probe conditions
2021
First-principles methods for time-resolved angular resolved photoelectron spectroscopy play a pivotal role in providing interpretation and microscopic understanding of the complex experimental data and in exploring novel observables or observation conditions that may be achieved in future experiments. Here we describe an efficient, reliable and scalable first-principles method for tr-ARPES based on time-dependent density functional theory including propagation and surface effects usually discarded in the widely used many-body techniques based on computing the non-equilibrium spectral function and discuss its application to a variety of pump–probe conditions. We identify four conditions, dep…
Search for lepton flavour violation in the e mu continuum with the ATLAS detector in root s=7 TeV pp collisions at the LHC
2012
This paper presents a search for the t-channel exchange of an R-parity violating scalar top quark ([~ over t] ) in the e[superscript ±]μ[superscript ∓] continuum using 2.1 fb[superscript −1] of data collected by the ATLAS detector in s√=7 TeV pp collisions at the Large Hadron Collider. Data are found to be consistent with the expectation from the Standard Model backgrounds. Limits on R-parity-violating couplings at 95 % C.L. are calculated as a function of the scalar top mass ( m[subscript bar over t]). The upper limits on the production cross section for pp→eμX, through the t-channel exchange of a scalar top quark, ranges from 170 fb for m[subscript ~ over t]=95 GeV to 30 fb for m[subscrip…
Option Pricing and Hedging in the Presence of Transaction Costs and Nonlinear Partial Differential Equations
2008
In the presence of transaction costs the perfect option replication is impossible which invalidates the celebrated Black and Scholes (1973) model. In this chapter we consider some approaches to option pricing and hedging in the presence of transaction costs. The distinguishing feature of all these approaches is that the solution for the option price and hedging strategy is given by a nonlinear partial differential equation (PDE). We start with a review of the Leland (1985) approach which yields a nonlinear parabolic PDE for the option price, one of the first such in finance. Since the Leland's approach to option pricing has been criticized on different grounds, we present a justification of…
A method for genome-wide analysis of DNA helical tension by means of psoralen-DNA photobinding
2010
The helical tension of chromosomal DNA is one of the epigenetic landmarks most difficult to examine experimentally. The occurrence of DNA crosslinks mediated by psoralen photobinding (PB) stands as the only suitable probe for assessing this problem. PB is affected by chromatin structure when is done to saturation; but it is mainly determined by DNA helical tension when it is done to very low hit conditions. Hence, we developed a method for genome-wide analysis of DNA helical tension based on PB. We adjusted in vitro PB conditions that discern DNA helical tension and applied them to Saccharomyces cerevisiae cells. We selected the in vivo cross-linked DNA sequences and identified them on DNA …
Advanced Virgo Status
2015
Abstract The detection of a gravitational wave signal in September 2015 by LIGO interferometers, announced jointly by LIGO collaboration and Virgo collaboration in February 2016, opened a new era in Astrophysics and brought to the whole community a new way to look at - or “listen” to - the Universe. In this regard, the next big step was the joint observation with at least three detectors at the same time. This configuration provides a twofold benefit: it increases the signal-to-noise ratio of the events by means of triple coincidence and allows a narrower pinpointing of GW sources, and, in turn, the search for Electromagnetic counterparts to GW signals. Advanced Virgo (AdV) is the second ge…
Trigger and aperture of the surface detector array of the Pierre Auger Observatory
2010
The surface detector array of the Pierre Auger Observatory consists of 1600 water-Cherenkov detectors, for the study of extensive airshowers (EAS) generated by ultra-high-energy cosmic rays. We describe the trigger hierarchy, from the identification of candidates howers at the level of a single detector, amongst a large background (mainly random single cosmic ray muons), up to the selection of real events and the rejection of random coincidences. Such trigger makes the surface detector array fully efficient for the detection of EAS with energy above 3 x 1018 eV, for all zenith angles between 03 and 603, independently of the position of the impact point and of the mass of the primary particl…
Zināšanu vadīšanas metožu pilnveidošana organizācijās
2013
Elektroniskā versija nesatur pielikumus
The Voyage of Metals in the Universe from Cosmological to Planetary Scales: the need for a Very High-Resolution, High Throughput Soft X-ray Spectrome…
2019
Metals form an essential part of the Universe at all scales. Without metals we would not exist, and the Cosmos would look completely different. Metals are primarily born through nuclear processes in stars. They leave their cradles through winds or explosions, and then start their journey through space. This can lead them in and out of astronomical objects on all scales, ranging from comets, planets, stars, entire galaxies, groups and clusters of galaxies to the largest structures of the Universe. Their wanderings are fundamental in determining how these objects, and the entire universe, evolve. In addition, their bare presence can be used to trace what these structures look like. The scope …
EDGE: explorer of diffuse emission and gamma-ray burst explosions
2009
How structures on various scales formed and evolved from the early Universe up to present time is a fundamental question of astrophysical cosmology. EDGE will trace the cosmic history of the baryons from the early generations of massive star by Gamma-Ray Burst (GRB) explosions, through the period of cluster formation, down to very low redshifts, when between a third and one half of the baryons are expected to reside in cosmic filaments undergoing gravitational collapse by dark matter (Warm Hot Intragalactic Medium: WHIM). In addition EDGE, with its unprecedented observational capabilities, will provide key results on several other topics. The science is feasible with a medium class mission …
Effective field theory search for high-energy nuclear recoils using the XENON100 dark matter detector
2017
International audience; We report on weakly interacting massive particles (WIMPs) search results in the XENON100 detector using a nonrelativistic effective field theory approach. The data from science run II (34 kg×224.6 live days) were reanalyzed, with an increased recoil energy interval compared to previous analyses, ranging from (6.6–240) keVnr. The data are found to be compatible with the background-only hypothesis. We present 90% confidence level exclusion limits on the coupling constants of WIMP-nucleon effective operators using a binned profile likelihood method. We also consider the case of inelastic WIMP scattering, where incident WIMPs may up-scatter to a higher mass state, and …